MethodsHow to obtain sharper gel bands than your neighbour; how to efficiently design probes for microarrays; how to isolate as much RNA as possible;... Researchers describe proven experimental protocols that you won't find in standard manuals.
NEW: Brain organoids (4.2017)
Organoids are produced when cells in 3D culture organise themselves into structures similar to real organs. Several organs have been mimicked in this way. However, when it was announced that you could pull the same trick to make not just any organ but real brains, it was not surprising that the popular press became interested. So, just how convincing are these “mini-brains” – and what can we do with them? more
NEW: Method Special: Single Cell Analysis (4.2017)
For centuries, biologists have preferred to analyse cells in large numbers, averaging out the results. But now things are beginning to change and we are starting to pay closer attention to the idiosyncratic properties of individual cells. Why is this happening – and in which direction is it taking us? more